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The SKYSCAN 1276 CMOS Edition has an unrivalled combination of high resolution, big image size, round and spiral (helical) scanning and reconstruction, and low dose imaging.
This high performance, stand-alone, fast, desktop in vivo microCT offers continuously variable magnification for scanning small laboratory animals (mice, rats etc.) and biological samples. An optional Large Animal Transport System (LATS) is available which enables the system to mount also large animals including rabbits.
(Please note: At this moment, we distribute this device only in Switzerland.)
X-ray micro-computed tomography (μCT) is one of the most advanced methods for getting 3D insights into samples of any material, any shape, and any size with little to no sample preparation, including small laboratory animals.
Bruker, a pioneer of microCT, has made this technology easier and more accessible for everyone by offering unparalleled in vivo 3D X-ray microtomography in a desktop format with the SKYSCAN 1276 CMOS high-resolution in vivo microCT. A single scan is all you need to reveal the complete internal 3D structure of your animal or sample non-destructively.
Counting on several hundreds of microCT installations worldwide, the SKYSCAN 1276 CMOS builds on this trusted platform and incorporates the latest X-ray technologies to bring microCT to the next level.
SKYSCAN 1276 CMOS Edition builds on the trusted SKYSCAN 1276 platform and integrates the latest X-ray technologies. Its state-of-art 16 megapixel sCMOS X-ray detector provides high-contrast images with superior resolution. The extended detector field of view and enhanced sensitivity for X-rays result in up to twice shorter scan times.
The extraordinary native resolution of up to 7,800 x 7,800 pixels per slice allows zooming into any part of the 3D volume without rescanning the sample. The new Clean Image(TM) scan mode significantly reduces typical CT artefacts right from the start, thus providing great quality images without cumbersome posteriori corrections.
This top performance is paired with low cost of ownership. Our desktop SKYSCAN 1276 CMOS Edition can be placed on any laboratory desk and consequently does not occupy a lot of expensive lab space. A standard domestic power plug is all you need to start running the instrument, no water chiller or additional compressor. There are also no further hidden costs as the industry-grade sealed X-ray source is maintenance-free.
| Feature | Benefit |
| Integrated temperature support and physiological monitoring | Ensures animal well-being throughout the imaging session, and consistency between animals within a study. |
| Integrated inhaled anesthesia | Ensures ease of animal handling and consistent plane of anesthesia gas |
| 75 x 310 mm Field of View | Allows full body mouse and rat scanning |
| Variable Magnification | Allows scanning bone and tissue samples with high spatial resolution down to 2.8 µm pixel size |
| 3D.SUITE Software | This extensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization. |
| On-Screen Real-Time Dose Meter | The SkyScan1276 control software includes a real-time on-screen dose meter. It indicates an estimation of the dose absorbed by the animal body during scanning. The dose meter shows accumulated dose or dose rate.
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| X-ray Source | 40-100 kV, 20 W, < 5 µm spot size at 4 W |
| X-ray Detector | 16 Megapixel sCMOS Camera, 4096 x 4096 pixels |
| Spatial Resolution | 2.8 µm smallest pixel size 6 μm details resolved with more than 10% contrast |
| Image Formats | Up to 7800 x 7800 x 2500 pixels after a single scan |
| Scanning Space | 75 mm in diameter, up to 310 mm in length |
| Integrated Physiological Monitoring | Real-time motion detection (5 MP color camera) ECG, breathing detection, temperature stabilization All signals digitized in 16 bit with up to 120 samples per second |
| Radiation Safety | < 1 µSv/h at any place of the instrument surface |
| System Dimensions | W x D x H: Weight: 360 kg |
The 3D.SUITE Software – A perfect match for SKYSCAN 1276 CMOS Edition
Intuitive, simple, yet powerful – the 3D.SUITE software that comes with every SKYSCAN 1276 CMOS EDITION is designed to inspire finding out what’s inside. With the help of Genius Mode, even a novice user can intuitively start scanning right away. It helps optimize the scan conditions by choosing the appropriate filter and X-ray energy to achieve optimal image contrast, and by selecting the optimum exposure time and rotation step for efficient scanning.
The SKYSCAN 1276 CMOS EDITION is supplied with a GLP module, which allows administration of user rights in 3 levels and implementation of the necessary data protection according to GLP requirements.
NRECON | Reconstruction Software
The acquired 2D projection images are transformed into 3D volumes by the reconstruction software NRECON. Typical CT artefacts, such as beam hardening, ring artefacts and misalignment, are easily corrected. The SKYSCAN 1276 CMOS EDITION is supplied with GPU accelerated reconstruction providing results up to 10 times faster than traditional CPU-based reconstruction. GPU acceleration supports both conventional round CT and helical scanning.
DATAVIEWER | Slice-by-slice Inspection
DATAVIEWER allows inspection of the reconstructed 3D volume using orthogonal slices in any direction. Objects can be rotated, repositioned, and resliced using their new orientation for more convenient visualization and saving of more efficient subvolumes. The software includes intuitive tools for measurement of 3D distances. 2D and 3D image registration enables the exact alignment of multiple scans of the same sample, acquired at different times.
CTVOX | Realistic Visualization by Volume Rendering
CTVOX is an easy-to-use volume rendering package that provides precise control of visualization parameters, ensuring a realistic representation of all types of samples. CTVOX offers intuitive manipulation of the point-of-view, virtual slicing through objects, and full control of light, shadow, and surface properties. Creating attractive cover images and impressive movies has never been this easy.
CTAN | 2D & 3D Image Analysis
Built over two decades based on direct feedback from scientists all over the world, CTAN is one of the most frequently used programs for quantitative image analysis. This package includes an extensive number of tools for region-of-interest selection, image segmentation and 3D measurements. Using the comprehensive library of embedded plugins or user-customized protocols, quantifying complex microstructures such as porosity, thickness, orientation, and many other properties is an easy task. Large sets of objects can simply be studied by automated batch analysis.
CTVOL | Built-in Surface Rendering
Surface models can be visualized in CTVOL, a flexible 3D viewing environment. Volumes can be exported in STL format, to allow 3D printing of the acquired scan data or further use in CAD and modelling programs.
Mineralized tissue analysis
Total Body Imaging
Lung and Cardiac dynamic imaging
Ex vivo sample analysis
